Some people believe CBD oil is safe and well-tolerated. Read about the side effects you can expect and what to be aware of. Can CBD Oil Make You Dizzy? Most people enjoy the benefits of CBD oil without experiencing any of the possible side effects, but not everyone is that lucky. Getting dizzy when using CBD hemp What Are The Side Effects of CBD Gummies? CBD gummies are a great way to take CBD without making much impact to your daily routine. These edible products are convenient, tasty, and discreet. You
7 CBD Oil Side Effects You Should Watch Out For
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CBD oil is believed to be generally safe and well-tolerated, but it is not free of side effects. Read on to learn which adverse effects you should watch out for when using CBD oil, how the delivery form influences them, and what you can do to reduce your risk.
CBD Oil Side Effects
First, it is important to remember that CBD oil is considered experimental and investigational and far more clinical studies are needed before we can make any firm conclusions about its supposed benefits .
Similarly, it’s an insufficiently investigated supplement with a relatively unknown safety profile. The list of side effects listed in this article is, therefore, not a definite one.
So, make sure to speak with your doctor before starting on a CBD oil regimen.
With the recent legalization of CBD oil in many states worldwide, its popularity is booming and people are taking it for not only its FDA-approved use for seizures, but also conditions such as :
An advantage of CBD oil is that it’s considered generally safer and causes fewer adverse effects than the drugs typically used for these conditions. Chronic doses of up to 1500 mg/day were tolerated well in multiple studies [3+, 4].
Unlike THC, CBD doesn’t cause behavioral and psychological side effects. What’s more, it may even reduce some of them such as anxiety, psychosis, and memory loss [5, 6, 7, 8].
CBD oil is believed to cause fewer side effects than THC and most prescription drugs, even at high doses.
Nevertheless, there are some potential side effects of CBD oil that you should watch out for. Below is a detailed overview of the most common ones.
1) Dry Mouth
Whether you use them for recreational or medicinal purposes, cannabis products will often make your mouth feel as if it were stuffed with cotton balls. Almost 12% of 1500 people responding to a survey about CBD use experienced dry mouth, making it the most common adverse effect .
Stimulation of the CB1 and CB2 receptors in the salivary glands reduces saliva secretion, which makes the mouth feel dry. The well-known cannabis compound THC activates these receptors directly. In turn, CBD raises the levels of an activator naturally produced in the body – the cannabinoid anandamide [9, 10, 11, 12].
2) Digestive Issues
Both CBD oil supplements and the FDA-approved CBD medicine Epidiolex have been reported to cause digestive issues such as [2, 4]:
- Nausea and vomiting
- Increased or reduced appetite
- Weight loss or gain
Because preliminary research suggests that CBD improves rather than causes nausea and diarrhea, these effects most likely result from the irritating effects of other ingredients (e.g., carrier oils) on the bowels [13, 14, 15].
Alternatively, the loose regulation of supplements may allow for excessive CBD levels in products or harmful contaminants such as pesticides, heavy metals, and solvents [16+, 17].
In turn, the endocannabinoid system has a role in promoting appetite. The mixed effects of CBD on appetite and weight seen in different studies may be due to its dual effect: it blocks the CB1 and CB2 receptors but boosts the levels of their activator anandamide [18, 19, 11].
If you experience digestive issues from using CBD oil, tell your doctor. He or she may recommend reducing the dose or shifting to another brand.
Contaminants and additives are likely responsible for the digestive side effects of low-quality CBD oil: nausea, vomiting, diarrhea, and appetite and weight changes.
3) Drowsiness and Fatigue
People taking CBD oil often report feeling sleepy and tired. Indeed, this side effect was observed in early clinical trials and one of the most common uses of CBD oil is to improve sleep disorders [20+].
If the symptoms are very severe, you shouldn’t drive or operate heavy machinery.
The effect of CBD on sleep seems to be biphasic: high doses may increase sleeping time, lower amounts may promote wakefulness. Additionally, levels of endocannabinoid receptors depend on the circadian rhythm. This may explain why CBD tends to cause drowsiness later in the day but has the opposite effect in the morning [21, 22, 23].
CBD oil may make you feel sleepy, especially if you take high doses at night. Low morning doses, on the contrary, seem to increase wakefulness.
High doses of CBD lowered blood pressure in a small trial on 9 people. In turn, THC seems to have a more complex effect: it slightly raises blood pressure in people lying down but increases the risk of sudden blood pressure drops when standing up [24, 25+].
As a result, a common adverse effect of CBD – both alone and with equal amounts of THC (nabiximols) – is feeling dizzy and light-headed [26, 27, 28].
If your blood pressure drops too much, you may faint. The risk is especially high in people diagnosed with low blood pressure or on blood pressure medications – such as diuretics, ACE inhibitors, and beta-blockers. These people should be especially cautious with CBD oil and never try it out without discussing it with their doctor.
CBD oil, alone or with THC, may reduce blood pressure. This can make you feel dizzy and light-headed, especially if you are prone to blood pressure drops.
5) Possible Liver Damage
Several trials testing CBD for seizures found possible liver damage (high transaminases ALT and AST) in 9-25% of the people. The risk increased with the dose and was highest in people also taking the anti-seizure drug valproate, which is known to cause liver injuries [29+, 30, 31, 32, 33, 34].
Similarly, CBD caused signs of liver toxicity (high transaminases, alkaline phosphatase, and bilirubin) in mice and dogs. However, the doses were generally higher than those used in human trials [35, 36, 37].
Make sure to talk to your doctor, especially if you are taking valproate, and never exceed the recommended CBD oil dose to reduce your risk of liver damage.
CBD oil may cause liver damage at very high doses and in people prescribed the anti-seizure drug valproate.
CBD is often used to curb anxiety, although research suggests it has “inverted U-shaped” effects: moderate doses, but not low or high amounts, may be effective for a range of anxiety disorders and stressful situations [38, 39].
In contrast, very high doses may even trigger anxiety and irritability. This was the case in 7-9% of the children in 2 clinical trials using CBD for seizures and autism [40, 41].
The effect probably involves the TRPV1 receptor, the activation of which increases the brain’s response to stressful situations .
CBD boosts the naturally-produced cannabinoid anandamide. While moderate anandamide levels activate CB1 receptors and curb anxiety, high amounts may worsen it by binding to TRPV1. CBD also activates this receptor directly, further contributing to the potential anxiety-triggering effects [43, 44, 11, 45].
7) Immune Suppression
CBD may reduce the immune response. It prevents T cells from dividing, migrating to inflammation sites, and producing pro-inflammatory cytokines. This may be beneficial in people with autoimmune conditions such as rheumatoid arthritis or multiple sclerosis [46, 47, 48, 49, 50, 51, 52].
The downside of blocking the immune response is that it may make people with weakened immune systems more prone to infections. Thus, people on immunosuppressants or with conditions such as HIV, diabetes, and Down syndrome might want to avoid it .
CBD oil seems to reduce the immune response, which may make people with a weak immune system more prone to infections.
CBD didn’t damage the kidneys in clinical trials. In fact, researchers believed it protected against kidney injury and inflammation in numerous animal studies [54, 55, 56, 57, 58]. Remember that larger and better designed clinical trials are needed before these findings are conclusive.
Though more clinical trials are needed, the current evidence suggests CBD oil will not harm your kidneys at normal doses.
On the other hand, people with kidney disease should probably avoid THC-containing medical marijuana without consulting a doctor.
According to a recent review, THC may worsen kidney health and increase urination by activating CB1 receptors. Remember that, unlike THC, CBD blocks these receptors. However, CBD may indirectly activate them by increasing anandamide levels in the body [59+].
Lastly, avoid synthetic cannabinoids at all costs (products like “spice” and “K2” sold in smoke shops). These chemicals caused sudden and severe kidney injury in several cases [59+].
Unlike THC and synthetic cannabinoids, CBD oil probably does not cause side effects on the kidneys; some researchers believe it might even be protective.
Are You at Risk of CBD Oil Side Effects?
CBD altered the levels of two drug transporters in placental cells. This suggests that taking CBD oil during pregnancy may increase the exposure of the fetus to any drugs that the mother takes. Pregnant women should avoid CBD oil in any case, since safety data are lacking .
Taking THC-containing CBD oil during pregnancy and breastfeeding is particularly dangerous, since THC may reduce growth and cause brain developmental anomalies in babies [61+].
Because there are no studies testing its safety in children below 2 years old, it’s better to avoid giving them CBD oil unless prescribed by a doctor.
CBD is thought to be safe in older children, but they may be more sensitive to THC and toxic contaminants such as heavy metals and pesticides than adults. Be sure to use high-quality, THC-free CBD in children and consult the doctor first.
Pregnant women and children under 2 years old should avoid CBD oil due to the lack of safety data; THC during pregnancy is known to be dangerous.
Most drugs are broken down by liver enzymes. Among them, cytochrome (CYP) P450 plays a key role. A single CBD dose blocks several CYP enzymes, such as:
By doing so, it may slow the breakdown of several drugs and enhance their effects [62, 63, 64, 65, 66].
Indeed, CBD reduced the breakdown of the sedative hexobarbital, the anti-seizure drug clobazam, and the blood thinner warfarin in humans. It had the same effect on the immunosuppressant cyclosporin and the cannabis compound THC in cells [67, 68, 69, 70].
On the other hand, repeated CBD doses can increase the levels of some enzymes of this group and reduce the effects of the drugs they break down [71, 72, 73, 74].
Plus, CBD itself is broken down by CYP enzymes, especially by CYP34A and CYP2C19. Drugs that block these enzymes (such as ketoconazole and ritonavir) will enhance its effects, while those that activate them (such as phenobarbital and rifampicin) will have the opposite effect [75, 4].
If you are on prescription medication and plan to use CBD oil, ask your doctor about potential interactions and dose readjustment. Additionally, avoid combining CBD oil with grapefruit or other supplements that block the same liver enzymes (such as St John’s wort or watercress).
CBD oil can block or activate liver enzymes that metabolize drugs. This may increase the side effects of both CBD oil and the medication you’re taking.
How Does the Delivery Form Influence CBD Oil Side Effects?
While rapid-release forms (mouth sprays and oil tinctures) deliver CBD directly into your bloodstream, slow-release forms (capsules, edibles, and teas) have to pass your digestive system first. This means their ingredients may irritate your bowels and give you nausea and diarrhea [76+, 77].
However, rapid-release forms will release CBD faster, so you may experience both wanted and unwanted effects sooner [76+, 77].
And since tinctures and sprays are directly applied in the mouth, they will quickly reach the salivary glands and cause dry mouth. Mouth sprays may also cause a stinging sensation and even burns, especially if they contain alcohol [9, 78].
Capsules and edibles are more likely to cause digestive side effects, while mouth sprays and tinctures more frequently cause dry mouth.
Vapes bypass the digestive system without irritating your bowels, but they may trigger the other adverse effects faster [76+, 77].
Vaping is considered safer than smoking cigarettes or joints because the oil is heated at lower temperatures that produce fewer toxic byproducts [76+ 79].
However, the additives used as flavorings and thinning agents in vaping oils may still pose some hazards. Although they are normally food-grade, they may release harmful compounds (including the cancer-causing formaldehyde) when vaporized. Their heavy use may lead to [80, 79, 81+]:
- Dry throat
- Lung injury
- Fat particles entering the lungs (lipoid pneumonia – rare)
For instance, one man developed severe lung damage from vaping CBD oil [82+].
Creams & Gels
Creams and gels act locally on the application site and don’t release CBD into the gut or bloodstream. This means they will not cause most of the adverse effects previously described [76+].
However, they may cause allergic reactions with itching, redness, and rashes on the skin. It’s important to note that the reactions can be caused by either CBD or other ingredients in the formulation [83+, 84+].
How to Reduce Your Risk of Side Effects from CBD Oil
1) Drink More Water
The best way to reduce dry mouth when using CBD oil is to drink plenty of water and other hydrating liquids before, during, and after consumption.
2) Find Additive-Free Products
You can reduce the risk of digestive issues by choosing forms that bypass the gut and directly release CBD into your bloodstream such as vapes, mouth sprays, and oil tinctures. High-quality oils without additives may also irritate your bowels less.
3) Take it Before Sleep
If you feel drowsy or light-headed after taking CBD oil, you may need to reduce the dose or take it only before sleep.
4) Increase Wakefulness Naturally
Drinking coffee or tea will help you both stay awake and raise your blood pressure, but it also causes many side effects. Try to get more sunlight first thing in the morning, as it will energize you and help you get better sleep at night. We talk about other natural ways to increase wakefulness in this post.
5) Support Your Liver
Avoid combining CBD with the anti-seizure drug valproate. Additionally, make sure not to exceed the dose and regularly monitor your liver function to reduce your risk of liver damage. Eggs (choline), artichokes, NAC, and probiotics also support liver health. Read more foods and supplements that are good for the liver here.
6) Don’t Take Megadoses
Only very high CBD doses may cause irritability. Make sure not to exceed the dose and try reducing it if you notice this symptom.
7) Monitor Your Immune Response
If you have a weakened immune system, you should consult your doctor before taking CBD oil. You may need to avoid CBD or take a lower dose.
Additionally, you may also want to look into balancing your Th1/Th2 immune response. If you have a slightly weaker immune system and are prone to allergies, you are probably Th2-dominant.
To reduce your risk of CBD oil side effects, avoid products with additives, drink plenty of water, get sunlight during the day, and support your liver and gut health.
Always make sure to speak with your physician before starting on a CBD oil regimen.
CBD oil is thought to be safe and most people seem to tolerate it well.
Low-quality products may contain additives and toxins that can irritate the lungs when vaped and the gut when taken orally. Choose high-quality products to reduce your risk.
Additionally, CBD oil can make you feel drowsy and lightheaded. If you feel tired after taking CBD oil, lower your dose or use it only before sleep. Look to also increase your wakefulness naturally by getting more sunlight during the day.
High doses may damage the liver, but likely only in people taking the anti-seizure medication valproate. Monitor your liver enzymes and look into natural ways to protect your liver.
Avoid CBD oil if you have a weak immune system, as it might make you more prone to infection.
If you take prescription drugs, consult your doctor. Many drugs can interact with CBD oil and increase the risk of side effects.
Pregnant women and children should avoid CBD oil until more safety data are available.
Some people have genes that make them more likely to experience inflammation. Check out SelfDecode’s Inflammation DNA Wellness Report for genetic-based diet, lifestyle, and supplement tips that can help reduce inflammation levels. The recommendations are personalized based on YOUR DNA.
About the Author
Carlos spent 9 years in the laboratory investigating mineral transport in plants. He then started working as a freelancer, mainly in science writing, editing, and consulting. Carlos is passionate about learning the mechanisms behind biological processes and communicating science to both academic and non-academic audiences. He strongly believes that scientific literacy is crucial to maintain a healthy lifestyle and avoid falling for scams.
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Can CBD Oil Make You Dizzy?
Most people enjoy the benefits of CBD oil without experiencing any of the possible side effects, but not everyone is that lucky.
Getting dizzy when using CBD hemp oil is one of the most common side effects people face, and this guide helps you understand why it happens and what you can do to prevent it. Using these tips lets you take advantage of the health benefits of CBD without worrying about getting dizzy.
Table of Contents
- Why CBD Oil Can Make You Dizzy
- Combating the Problem and Staying Sharp
- Speaking With a Doctor
- Final Thoughts
Why CBD Oil Can Make You Dizzy
Learning why CBD oil can make you dizzy is a great place to start if you want to use it without dealing with the issue. When you take CBD oil, it can lower your blood pressure, which is a powerful benefit for a lot of people.
The problem occurs if you already have normal or low blood pressure when you begin taking CBD oil. In those cases, it can lower your blood pressure enough that you get dizzy or even lightheaded. The good news, though, is that most people only feel dizzy for a few minutes after taking their CBD oil.
Combating the Problem and Staying Sharp
If your dizziness lasts for more than a few minutes or if you want to stop yourself from getting dizzy in the first place, start by lowering your dose of CBD oil each day until you no longer get dizzy. The goal is to take enough of the CBD oil to get the benefits you want without facing the downsides, which means finding the right balance for your unique body and needs.
If lowering your dose causes you to lose the benefits, you are not out of luck yet. Try finding the lowest dose that lets you enjoy the rewards for which you have been looking. Next, try sitting or lying down for a few minutes after taking the CBD. Eating a light snack is another excellent way to combat the dizzy feeling and stay sharp.
Speaking With a Doctor
Speaking with your doctor is important if you experience anything more than a light or mild dizzy feeling that lasts for more than a few minutes. While the odds of facing a serious medical issue are low when taking CBD, talking with your doctor is always the safe bet if you care about your overall well-being.
Your doctor will monitor your blood pressure and test you for other conditions that might be causing you to feel dizzy. Maintaining open and honest communication with your doctor is important. It lets your doctor give you viable advice that keeps you in top shape for as long as possible.
Quality hemp oil from a reputable CBD company can help people treat and prevent a range of harmful conditions. It also improves their quality of life by providing them with several benefits, including improved mood. Even though CBD hemp oil can do wonders to improve your overall health, you could encounter one or more side effects along the way. CBD oil can cause some people to get dizzy by lowering their blood pressure, but there are steps you can take to keep the problem at bay.
What Are The Side Effects of CBD Gummies?
CBD gummies are a great way to take CBD without making much impact to your daily routine. These edible products are convenient, tasty, and discreet. You can enjoy the benefits of a CBD gummy from anywhere at any time. Whether you need to relax after a long day at work, or if you want to improve your quality of sleep each night, CBD gummies may be just what you need.
As a whole, CBD shows promise as a possible treatment for many common ailments. Research has shown that CBD may be effective in minimizing chronic pain, stress, anxiety, depression, and acne. The cannabinoid has also shown promising anti-inflammatory and anti-seizure properties, which means CBD may be a possible treatment for seizure disorders.
While there’s a lot of good that surrounds CBD gummies, there are risks that you should be aware of. Here are some of the most common CBD gummies side effects, as well as what you can do to minimize experiencing them.
CBD is a very calming and relaxing compound. While it typically doesn’t cause feelings of tiredness or drowsiness, it is a possibility. As with any compound, how CBD affects you may differ from how it affects someone else. For instance, some people experience a wake-inducing effect after taking CBD, which makes them feel more alert and energetic. For others, the cannabinoid produces an opposite reaction, where users feel drowsy.
If you notice that you feel tired after taking CBD, avoid driving a vehicle or operating any heavy machinery. Because CBD gummies affects your energy, it is to protect your health and safety as well as the safety of those around you.
To minimize drowsiness, minimize the amount of CBD that you’re consuming.
Dry mouth is a common side effect that is experienced when using any cannabinoid, including CBD. Dryness of the mouth can occur if cannabinoids are consumed, smoked, or vaped.
You may notice that your mouth is dry when using CBD because of how cannabinoids interact with the endocannabinoid system. This system has receptors in the salivary glands, and when activated, the secretion of saliva from the glands can be inhibited.
According to one study, the submandibular gland that produces more than 60% of saliva has cannabinoid receptors. Anandamide, which is an endocannabinoid in the body, is linked to dry mouth. This happens when the endocannabinoid interacts with the submandibular receptors, which then block the signals from the nervous system that tells the gland to produce saliva.
Dizziness & Lightheadedness
This is a very rare side effect, but it’s possible that you may feel dizzy or lightheaded after using CBD. This side effect is generally temporary and can be quickly relieved by drinking a caffeinated beverage such as coffee. This will allow your body to regain its balance.
If you feel dizzy after consuming CBD gummies, drink a cup of coffee, tea, or soda. It’s also important to drink plenty of water throughout the day when you take any kind of CBD product.
Drop in Blood Pressure
Many people who experience dizziness or lightheadedness experience this side effect because of a drop in blood pressure. CBD has been linked as being beneficial to helping those with heart disease and diabetes by lowering blood pressure.
This property of CBD is positive for the most part, but for people with normal blood pressure, it can cause a slight drop. This can lead to dizziness and lightheadedness.
If you suffer from low blood pressure or take medication to regulate your blood pressure, it’s best to refrain from taking CBD gummies. Always consult your doctor before adding CBD as part of your daily regimen.
Interaction with Prescription Drugs
Those taking any kind of prescription drug for a pre-existing health condition must consult with their doctor before taking CBD gummies. This is because CBD research has shown that the compound affects drug metabolism within the liver.
CBD impedes the activity of certain liver enzymes, namely cytochrome P450 enzyme system, which metabolizes pharmaceutical drugs. In the case of other prescription drugs, CBD may actually increase enzyme activity, which can also be dangerous.
This means that any drug that uses the CYP450 enzymes to metabolize may negatively interact with CBD. Some of the common drugs that CBD may interact with include:
- Calcium channel blockers
- Beta blockers
To protect your health, always check with your doctor to get medical clearance to take CBD gummies or any other kind of CBD product. This way you’re aware of any interactions and can prevent them as needed.
How to Minimize Side Effects
The good news is that all of the common CBD side effects are minimal. For most, they’re more so a nuisance than a risk or danger. What’s even better is the fact that there are ways you can minimize the chance that you’ll experience any side effects at all.
One of the first things you can do when taking CBD gummies is to use the appropriate dosage. If you’ve never taken CBD before, you’ll want to start with the lowest dosage possible. You can find many different CBD gummies available in low doses such as 5mg and 10mg.
Over time you can gradually increase your CBD dosage until you find your sweet spot. It’s best to start low and slow so that you avoid consuming too much CBD too quickly.
Another way to prevent side effects is to only buy high quality CBD products. Avoid CBD products sold at gas stations or other local convenience stores. The best place to find superior CBD gummies is online.
The CBD gummies you purchase should be made with USA-grown hemp and should have a reliable certificate of analysis (COA). This documentation identifies what a product consists of, to include cannabinoids, terpenes, flavonoids, as well as potential contaminants such as pesticides and heavy metals.
While research has shown that CBD offers all sorts of benefits, there are some side effects to be aware of. If you experience any of the side effects on this, lower your dosage or contact your doctor.